![]() ACE inhibitors reduce the pressure and flow further, which can be harmful for the kidneys. This is because diuretics remove some of the fluid from your blood which can reduce the pressure and flow of blood through the kidneys. If you are taking diuretics, you will be carefully monitored if you start taking ACE inhibitors. Your doctor will consider your overall health and any treatments you’re having before giving you any new medicines. They can occasionally interfere with certain health problems and medications. ACE inhibitors reduce the pressure in kidneys, so they leak less.ĪCE inhibitors are not suitable if you’re pregnant, breastfeeding or planning to get pregnant. They are particularly useful if you have diabetes and high blood pressure at the same time, or diabetes which has caused some kidney damage that causes them to leak protein into the urine, known as microalbuminuria. They can also be used for people with diabetes, heart failure, some types of kidney disease and after a heart attack. They’re often suitable if you’re under 55 and not of African or Caribbean descent, but can still be an option if that doesn’t apply to you. It can take some trial and error to find the right one or the right combination, and ACE inhibitors are often one of the first ones you will try, either on their own or alongside another one. If you have high blood pressure, your doctor or nurse might suggest you take medicines to lower it. With more fluid in the blood, there is more pressure on the blood vessel walls.ĪCE inhibitors allow your blood vessels to relax and widen, and for fluid to be removed from your blood and released in your urine, lowering you blood pressure. Angiotensin II also acts on the kidneys, causing them to keep water in your blood stream rather than releasing it in your urine. It makes the muscles in your blood vessel walls contract, making the blood vessels narrower so your blood has less space to flow through. Most have names that end in ‘pril’, for example, enalapril, lisinopril, perindopril and ramipril.ĪCE inhibitors stop your body from producing a hormone called angiotensin II, lowering the amount in your blood.Īngiotensin II raises your blood pressure in two ways. They work mainly by allowing the blood vessels to relax and widen so the blood has more space to flow through. ![]() ACE (angiotensin-converting enzyme) inhibitors are a type of medicine often used to treat high blood pressure.
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